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This is the fastest way to get help. Be sure to have all of your information ready before you call. Available options are based on your income, insurance, and the type of insulin you need. Before you call, plan to spend 20—30 minutes and be prepared to answer questions such as:. Find out who your manufacturer is by checking the company logo on your insulin vial or pen, and call using the numbers provided below.

Lilly Diabetes Solution Center Novo Nordisk Diabetes Care Find financial assistance and patient access support for Novo Nordisk products in the US.

6.1: Drugs Used In Diabetes

Sanofi Patient Assistance Program Sanofi provides unprecedented access to its insulins for one set monthly price. Want local support?

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Find a community health clinic or pharmacy in your area that may offer free or low-cost services and medications. If you have health insurance, be sure to ask if the discount program will interact with your coverage. The American Diabetes Association ADA recognizes that affordable access to insulin is a matter of life and death, every day for more than 7.

Human insulin formulations include long-acting insulins like NPH, which has a duration of hours, or regular insulin, which has a much quicker onset, as little as 30 minutes, and shorter duration. In select patients with proper monitoring, human insulin may be an option for those who struggle with affording their medications. In our white paper , published in Diabetes Care, we acknowledge that prescribing patterns have favored newer, more expensive insulins, and acknowledge that human insulin may be an appropriate alternative to more expensive analog insulins for some people with diabetes.

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If you're struggling with the cost of insulin, you're not alone. Be sure to talk to your healthcare team to learn about your options. Cost per item has changed little in the past four to five years for most drugs in this category, the exception being pioglitazone. Figure 3. Figure 4. The DPP-4 inhibitors have enjoyed enormous success: within the space of 10 years, annual volume has increased from 23 to 4.

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The GLP-1 receptor agonists are the second largest group of other anti-diabetic drugs. Introduced at about the same time as the DPP-4 inhibitors, prescribing has increased at about one-fifth of the rate for that group Figure 3 , but the rate of cost growth has been about half Figure 4.

These agents are the most expensive of the other antidiabetic drugs, with average costs per item two to three times greater than the DPP-4 inhibitors and SGLT2 inhibitors. This, the newest group of other anti-diabetic drugs, has also been a success.

— How conflicting guidelines, interests play a role in prescribing drugs

Table 2. The 6. They rank fourth by prescribing volume after metformin, sulphonylureas and other antidiabetic drugs , but have the highest annual cost Figures 1 and 2 and average net ingredient cost by group, not individual product of all. The statistics on insulin prescribing do not differentiate between their use for type 1 or type 2 diabetes.

Primary care diabetes prescribing rates: latest analysis shows continued rise in volume and cost

Several indicators suggest that the growth in prescribing for diabetes is likely to continue. First, the population eligible for treatment will grow.


The prevalence of diabetes in England is expected to increase to 9. Finally, the indications for drug treatment may broaden, or certain classes of antidiabetic agents may be preferred for some subgroups of patients, as evidence emerges of their impact on long-term outcomes. Two trials have recently shown that treatment can reduce cardiovascular mortality in patients with type 2 diabetes who are at high cardiovascular risk Table 3. However, non-fatal myocardial infarction, non-fatal stroke and admission for heart failure were not significantly less common than with placebo.

Liraglutide also significantly reduced the incidence of nephropathy but not retinopathy. The number of patients who would need to be treated NNT to prevent one primary endpoint event in three years was 66; the NNT for death from any cause was There was little difference between the two doses of empaglifl ozin, and differences between active treatment and placebo in the incidence of non-fatal myocardial infarction and stroke were not signifi cant. The NNT to prevent one primary endpoint event over three years was These very large cardiovascular outcome trials suggest that, in populations representative of people with type 2 diabetes, 6 GLP-1 receptor agonists and SGLT2 inhibitors can reduce cardiovascular death.

Further, it is possible that liraglutide and empagliflozin may offer advantages for different patient subgroups. By contrast, several trials suggest that the DPP-4 inhibitors have, at best, a neutral impact on cardiovascular outcomes. Prescribing for diabetes in primary care in England continues to increase and is still dominated by insulin analogues and metformin.

Improving Diabetes (Trial) - Prescribing HbA1c

Rapid growth in the use of newer drugs for type 2 diabetes has been led by the DPP-4 inhibitors but, as evidence emerges that GLP-1 receptor agonists and SGLT2 inhibitors reduce mortality in patients with cardiovascular risk factors, these agents are likely to have a greater role in the future.

NHS Digital. Prescribing for Diabetes. August Public Health England. Diabetes prevalence model for local authorities and CCGs. September National Institute for Health and Care Excellence. Type 2 diabetes in adults: management.

Marso SP, et al. Liraglutide and cardiovascular outcomes in type 2 diabetes. N Engl J Med ; — Zinman B, et al. Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes. N Engl J Med ;— Iglay K, et al.